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1

Structure elucidation and an investigation into the in vitro effects of hop acids on human cancer cells

Elizabeth Tyrrell, Roland Archer, G.A. Skinner, Kuldip Singh, Kay Colston, Catherine Driver

Journal:

Phytochemistry Letters

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

2

The synthesis and anticancer effects of a range of natural and unnatural hop β-acids on breast cancer cells

Elizabeth Tyrrell, Roland Archer, Matt Tucknott, Kay Colston, Grisha Pirianov, Dharahana Ramanthan, Rajdeep Dhillon, Alex Sinclair, G.A. Skinner

Journal:

Phytochemistry Letters

Year:

2012

Language:

english

File:

PDF, 444 KB

english, 2012

3

Plasma 25-hydroxy vitamin D concentrations, vitamin D receptor genotype and breast cancer risk in a UK Caucasian population

Lorraine C. Lowe, Michelle Guy, Janine L. Mansi, Clare Peckitt, Judith Bliss, Rosalind Given Wilson, Kay W. Colston

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 113 KB

english, 2005

4

Interaction of vitamin D analogs with signaling pathways leading to active cell death in breast cancer cells

Grisha Pirianov, Kay W Colston

Journal:

Year:

2001

Language:

english

File:

PDF, 506 KB

english, 2001

5

An Investigation into the Anticancer Effects and Mechanism of Action of Hop β-Acid Lupulone and Its Natural and Synthetic Derivatives in Prostate Cancer Cells

Mouratidis, Petros X. E., Colston, Kay W., Tucknott, Matthew L., Tyrrell, Elizabeth, Pirianov, Grisha

Journal:

Nutrition and Cancer

Year:

2013

Language:

english

File:

PDF, 424 KB

english, 2013

6

Sensitive induction of apoptosis in breast cancer cells by a novel 1,25-dihydroxyvitamin D3 analogue shows relation to promoter selectivity

Carina Danielsson, Ida S. Mathiasen, Sharon Y. James, Sepideh Nayeri, Claus Bretting, Christina Mørk Hansen, Kay W. Colston, Carsten Carlberg

Journal:

Journal of Cellular Biochemistry

Year:

1997

Language:

english

File:

PDF, 121 KB

english, 1997

7

The regulation of macrophage activity in congenitally athymic mice

A. Kay Sharp, M. Joseph Colston

Journal:

European Journal of Immunology

Year:

1984

Language:

english

File:

PDF, 446 KB

english, 1984

8

Doxycycline induces caspase-dependent apoptosis in human pancreatic cancer cells

Petros X.E. Mouratidis, Kay W. Colston, Angus G. Dalgleish

Journal:

International Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 1.12 MB

english, 2007

9

MCF-7/VDR: A new vitamin D resistant cell line

Christina Mørk Hansen, Lili Rohde, Mogens W. Madsen, Dann Hansen, Kay W. Colston, Grisha Pirianov, Pernille Kaae Holm, Lise Binderup

Journal:

Journal of Cellular Biochemistry

Year:

2001

Language:

english

File:

PDF, 420 KB

english, 2001

10

Inhibition of osteoblast function in vitro by aminobisphosphonates

Isabel R. Orriss, Michelle L. Key, Kay W. Colston, Timothy R. Arnett

Journal:

Journal of Cellular Biochemistry

Year:

2009

Language:

english

File:

PDF, 427 KB

english, 2009

11

The use of nasal calcitonin spray in the treatment of hypercalcaemia of malignancy

Mark Bower, Robert C. Stein, Anthea Hedley, Joanna Davenport, Kay Colston, R. Charles Coombes

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1991

Language:

english

File:

PDF, 204 KB

english, 1991

12

The immunomodulatory drug lenalidomide restores a vitamin D sensitive phenotype to the vitamin D resistant breast cancer cell line MDA-MB-231 through inhibition of BCL-2: potential for breast cancer therapeutics

Carole Brosseau, Kay Colston, Angus George Dalgleish, Christine Galustian

Journal:

Year:

2012

Language:

english

File:

PDF, 498 KB

english, 2012

13

The relationship between the insulin-like growth factor-1 system and the oestrogen metabolising enzymes in breast cancer tissue and its adjacent non-cancerous tissue

Yoon Mann Chong, Kay Colston, Wen G. Jiang, Anup K. Sharma, Keefah Mokbel

Journal:

Breast Cancer Research and Treatment

Year:

2006

Language:

english

File:

PDF, 371 KB

english, 2006

14

Zoledronic acid induces apoptosis and inhibits adhesion to mineralized matrix in prostate cancer cells via inhibition of protein prenylation

Jonathan P. Coxon, Grenville M. Oades, Roger S. Kirby, Kay W. Colston

Journal:

BJU International

Year:

2004

Language:

english

File:

PDF, 173 KB

english, 2004

15

Effect of Calcitonin on Vitamin D Metabolism

GALANTE, LEE, COLSTON, KAY W., MACAULEY, S. J., MACINTYRE, I.

Journal:

Year:

1972

File:

PDF, 360 KB

1972

16

The Regulation of Vitamin D Metabolism

COLSTON, KAY W., EVANS, IMOGEN M. A., BYFIELD, P. G. H., MATTHEWS, E. W., MACINTYRE, I., GALANTE, LEONORA

Journal:

Year:

1973

File:

PDF, 275 KB

1973

17

EB1089, a synthetic analogue of vitamin D, induces apoptosis in breast cancer cells in vivo and in vitro

Sharon Y. James, Elizabeth Mercer, Matthew Brady, Lise Binderup, Kay W. Colston

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 725 KB

english, 1998

18

Potentiation by vitamin D analogs of TNFα and ceramide-induced apoptosis in MCF-7 cells is associated with activation of cytosolic phospholipase A2

Pirianov, Grisha, Danielsson, Carina, Carlberg, Carsten, James, Sharon Y, Colston, Kay W

Journal:

Cell Death & Differentiation

Year:

1999

Language:

english

File:

PDF, 556 KB

english, 1999

19

Estrogen receptors and human bone cells: Immunocytochemical studies

Kay W. Colston, R.J.B. King, J. Hayward, D.I. Fraser, M.A. Horton, J.C. Stevenson, T.R. Arnett

Journal:

Journal of Bone and Mineral Research

Year:

1989

Language:

english

File:

PDF, 2.54 MB

english, 1989

20

Interaction of androgen and 1,25-dihydroxyvitamin D3: Effects on normal rat bone cells

Colin Gray, Kay W. Colston, Alan G. Mackay, M. Louise Taylor, Timothy R. Arnett

Journal:

Journal of Bone and Mineral Research

Year:

1992

Language:

english

File:

PDF, 488 KB

english, 1992

21

A SURVEY OF THE HORMONAL FACTORS THAT CONTROL CALCIUM METABOLISM

I. Maclntyre, Kay W. Colston, M. Szelke, E. Spanos

Journal:

Annals of the New York Academy of Sciences

Year:

1978

Language:

english

File:

PDF, 421 KB

english, 1978

22

Effects of synthetic vitamin d analogues on breast cancer cell proliferation in vivo and in vitro

Kay W. Colston, Surinder K. Chander, Alan G. MaCkay, R.Charles Coombes

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 1.00 MB

english, 1992

23

EB1089: A new vitamin D analogue that inhibits the growth of breast cancer cells in vivo and in vitro

Kay W. Colston, Alan G. Mackay, Sharon Y. James, Lise Binderup, Surinder Chander, R.Charles Coombes

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 703 KB

english, 1992

24

Separation of hydroxylated derivatives of vitamin D3 by high speed liquid chromatography (HSLC)

E.W. Matthews, P.G.H. Byfield, Kay W. Colston, Imogen M.A. Evans, Leonora S. Galante, I. MacIntyre

Journal:

Year:

1974

Language:

english

File:

PDF, 250 KB

english, 1974

25

Induction of apoptosis in breast cancer cells by apomine is mediated by caspase and p38 mitogen activated protein kinase activation

Lorraine C. Lowe, Siddhika G. Senaratne, Kay W. Colston

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 556 KB

english, 2005

26

Inhibition of Osteoblast function by bisphosphonates

Isabel R. Orriss, Michelle L. Key, Kay W. Colston, Timothy R. Arnett

Journal:

Year:

2008

Language:

english

File:

PDF, 62 KB

english, 2008

27

Biological actions of extra-renal 25-hydroxyvitamin D-1α-hydroxylase and implications for chemoprevention and treatment

Kelly Townsend, Katie N. Evans, Moray J. Campbell, Kay W. Colston, John S. Adams, Martin Hewison

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 202 KB

english, 2005

28

The immune response in paratuberculosis infection of small ruminants

C.J. Clarke, A. Colston, D. Little, J. Kay, H.M. Alzuherri, J.M. Sharp, C. Burrells

Journal:

Veterinary Immunology and Immunopathology

Year:

1996

Language:

english

File:

PDF, 57 KB

english, 1996

29

A study of immunological responses of sheep clinically-affected with paratuberculosis (Johne's disease): The relationship of blood, mesenteric lymph node and intestinal lymphocyte responses to gross and microscopic pathology

C. Burrells, C.J. Clarke, A. Colston, J.M. Kay, J. Porter, D. Little, J.M. Sharp

Journal:

Veterinary Immunology and Immunopathology

Year:

1998

Language:

english

File:

PDF, 770 KB

english, 1998

30

Interferon-gamma and interleukin-2 release by lymphocytes derived from the blood, mesenteric lymph nodes and intestines of normal sheep and those affected with paratuberculosis (Johne's disease)

C Burrells, C.J Clarke, A Colston, J.M Kay, J Porter, D Little, J.M Sharp

Journal:

Veterinary Immunology and Immunopathology

Year:

1999

Language:

english

File:

PDF, 165 KB

english, 1999

31

Mechanisms of bisphosphonate induced apoptosis in prostate cancer

Grenville Oades, Siddhika Senaratne, Ian Clarke, Roger Kirby, Kay Colston

Journal:

European Urology Supplements

Year:

2002

Language:

english

File:

PDF, 182 KB

english, 2002

32

Vitamin D and breast cancer risk

Journal:

Best Practice & Research Clinical Endocrinology & Metabolism

Year:

2008

Language:

english

File:

PDF, 218 KB

english, 2008

33

The role of vitamin D derivatives and retinoids in the differentiation of human leukaemia cells

Sharon Y. James, Marc A. Williams, Stephen M. Kelsey, Adrian C. Newland, Kay W. Colston

Journal:

Biochemical Pharmacology

Year:

1997

Language:

english

File:

PDF, 1.28 MB

english, 1997

34

REGULATION OF VITAMIN D: AN EVOLUTIONARY VIEW

I. MacINTYRE, KAY W. COLSTON, IMOGEN M. A. EVANS, EVELYNE LOPEZ, S. J. MacAULEY, JACQUELINE PIEGNOUX-DEVILLE, E. SPANOS, M. SZELKE

Journal:

Clinical Endocrinology

Year:

1976

Language:

english

File:

PDF, 567 KB

english, 1976

35

Nitrogen Containing Bisphosphonates Induce Apoptosis and Inhibit the Mevalonate Pathway, Impairing Ras Membrane Localization in Prostate Cancer Cells

OADES, GRENVILLE M., SENARATNE, SIDDHIKA G., CLARKE, IAN A., KIRBY, ROGER S., COLSTON, KAY W.

Journal:

The Journal of Urology

Year:

2003

Language:

english

File:

PDF, 915 KB

english, 2003

36

The role of bisphosphonates in breast cancer: Direct effects of bisphosphonates on breast cancer cells

Siddhika G Senaratne, Kay W Colston

Journal:

Breast Cancer Research

Year:

2001

Language:

english

File:

PDF, 100 KB

english, 2001

37

Effects of 1,25 dihydroxyvitamin D3 and its analogues on induction of apoptosis in breast cancer cells

James, Sharon Y., Mackay, Alan G., Colston, Kay W.

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1996

Language:

english

File:

PDF, 976 KB

english, 1996

38

EB 1089, a novel vitamin D analogue, has strong antiproliferative and differentiation inducing effects on cancer cells

Mathiasen, Ida S., Colston, Kay W., Binderup, Lise

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

1993

Language:

english

File:

PDF, 1002 KB

english, 1993

39

EFFECT OF PARATHYROID EXTRACT ON VITAMIN-D METABOLISM

Galante, Lee, Colston, Kay, Macauley, S., Macintyre, I.

Journal:

Year:

1972

Language:

english

File:

PDF, 537 KB

english, 1972

40

Effect of triiodothyronine on intestinal and kidney isoenzymes of alkaline phosphatase and on vitamin D metabolism in adult female rats

Colston, Kay, Cleeve, H.J.W.

Journal:

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry

Year:

1986

Language:

english

File:

PDF, 336 KB

english, 1986

41

Effect of prolactin on vitamin D metabolism

Spanos, E., Colston, Kay W., Evans, Imogen M.S., Galante, Leonora S., Macauley, S.J., Macintyre, I.

Journal:

Molecular and Cellular Endocrinology

Year:

1976

Language:

english

File:

PDF, 359 KB

english, 1976

42

1,25-DIHYDROXYVITAMIN D 3 AND MALIGNANT MELANOMA: THE PRESENCE OF RECEPTORS AND INHIBITION OF CELL GROWTH IN CULTURE

COLSTON, KAY, COLSTON, M. JOSEPH, FELDMAN, DAVID

Journal:

Year:

1981

Language:

english

File:

PDF, 433 KB

english, 1981

43

Extracellular Nucleotides Block Bone Mineralization in Vitro : Evidence for Dual Inhibitory Mechanisms Involving Both P2Y 2 Receptors and Pyrophosphate

Orriss, Isabel R., Utting, Jennifer C., Brandao-Burch, Andrea, Colston, Kay, Grubb, Barbara R., Burnstock, Geoffrey, Arnett, Timothy R.

Journal:

Year:

2007

Language:

english

File:

PDF, 437 KB

english, 2007

44

1,25-Dihydroxyvitamin D 3 Binding in Estrogen-Responsive Rat Breast Tumor*

COLSTON, KAY, WILKINSON, J. R., COOMBES, R. C.

Journal:

Year:

1986

Language:

english

File:

PDF, 852 KB

english, 1986

45

Organ Distribution of the Cytoplasmic 1,25- Dihydroxycholecalciferol Receptor in Various Mouse Tissues*

COLSTON, KAY, HIRST, MARGARET, FELDMAN, DAVID

Journal:

Year:

1980

Language:

english

File:

PDF, 917 KB

english, 1980

46

DEMONSTRATION OF A 1,25-DIHYDROXYCHOLECALCIFEROL CYTOPLASMIC RECEPTOR-LIKE BINDER IN MOUSE KIDNEY

COLSTON, KAY W., FELDMAN, DAVID

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1979

Language:

english

File:

PDF, 404 KB

english, 1979

47

DEMONSTRATION OF 1,25-DIHYDROXYVITAMIN D 3 RECEPTORS IN HUMAN SKIN BIOPSIES

FELDMAN, DAVID, CHEN, THERESA, HIRST, MARGARET, COLSTON, KAY, KARASEK, MARVIN, CONE, CHARLOTTE

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1980

Language:

english

File:

PDF, 387 KB

english, 1980

48

Retinoic Acid Enhances the Cytotoxic Effects of Gemcitabine and Cisplatin in Pancreatic Adenocarcinoma Cells

Pettersson, Filippa, Colston, Kay W., Dalgleish, Angus G.

Journal:

Year:

2001

Language:

english

File:

PDF, 4.63 MB

english, 2001

49

Antiproliferative Effects of CC-8062 and CC-8075 in Pancreatic Cancer Cells

Mouratidis, Petros X.E., Colston, Kay W., Bartlett, Jake Blake, Muller, George W., Man, Hon-Wah, Stirling, David, Dalgleish, Angus G.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.44 MB

english, 2009

50

Investigation of the Mechanisms by Which EB1089 Abrogates Apoptosis Induced by 9-cis Retinoic Acid in Pancreatic Cancer Cells

Mouratidis, Petros X. E, Dalgleish, Angus G, Colston, Kay W

Journal:

Year:

2006

Language:

english

File:

PDF, 654 KB

english, 2006